It is not uncommon for people with lupus to experience muscle aches and pain (myalgias) or have inflammation of certain muscle groups (myositis), which causes weakness and loss of strength. More than 90 percent of people with lupus will experience joint and/or muscle pain at some time during the course of their illness.1 More than half of the people who develop lupus mention joint pain as their first symptom. Muscle pain and muscle tenderness, especially during periods of increased disease activity (flare), occur in as many as 50 percent of those with lupus.
https://www.lupus.org/resources/how-lupus-affects-the-muscles-tendons-and-joints
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